Acute Kidney Injury in SARS-CoV-2 Infection: Direct Effect of Virus on Kidney Proximal Tubule Cells.

Authors :: Soleimani M
Source :: International journal of molecular sciences [Int J Mol Sci] 2020 May 05; Vol. 21 (9). Date of Electronic Publication: 2020 May 05.
Publication Year :: 2020
Abstract: Coronaviruses (CoVs), including Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and the novel coronavirus disease-2 (SARS-CoV-2) are a group of enveloped RNA viruses that cause a severe respiratory infection which is associated with a high mortality [...].<br />Competing Interests: The authors declare no conflict of interest.

Subjects :: Acute Kidney Injury physiopathology
Acute Kidney Injury prevention & control
Angiotensin II pharmacology
Angiotensin-Converting Enzyme 2
COVID-19
Cathepsins metabolism
Cell Death drug effects
Coronavirus Infections mortality
Coronavirus Infections pathology
Coronavirus Infections physiopathology
Creatinine blood
Critical Illness mortality
Endosomes drug effects
Endosomes enzymology
Endosomes metabolism
Humans
Hydrogen-Ion Concentration
Incidence
Kidney Tubules, Proximal physiopathology
Lysosomes drug effects
Lysosomes enzymology
Lysosomes metabolism
Pandemics
Peptidyl-Dipeptidase A metabolism
Pneumonia, Viral mortality
Pneumonia, Viral pathology
Pneumonia, Viral physiopathology
Receptors, Virus metabolism
SARS-CoV-2
Severe Acute Respiratory Syndrome blood
Severe Acute Respiratory Syndrome mortality
Severe Acute Respiratory Syndrome physiopathology
Virus Internalization
Virus Replication
Acute Kidney Injury mortality
Acute Kidney Injury virology
Betacoronavirus pathogenicity
Coronavirus Infections virology
Kidney Tubules, Proximal metabolism
Kidney Tubules, Proximal virology
Pneumonia, Viral virology

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