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A Cross-Sectional Study of Seroprevalence of Strongyloidiasis in Pregnant Women (Peruvian Amazon Basin).
- Source :
-
Pathogens (Basel, Switzerland) [Pathogens] 2020 May 04; Vol. 9 (5). Date of Electronic Publication: 2020 May 04. - Publication Year :
- 2020
-
Abstract
- Strongyloidiasis is a soil-transmitted helminthiasis with a high global prevalence.<br />Objectives: We aimed to evaluate the prevalence of Strongyloides stercoralis infection and assess strongyloidiasis serology as a screening technique in the Peruvian Amazon.<br />Material and Methods: We performed a cross-sectional study of strongyloidiasis in 300 pregnant women in Iquitos (Peru) from 1 May 2019 to 15 June 2019. Women were tested using serology (Strongyloides IgG IVD-ELISA kit) as an index test and the modified Baermann technique and/or charcoal fecal culture as the parasitological reference standard.<br />Results: The reference tests showed S. stercoralis in the stool of 30 women (prevalence: 10%; 95% confidence interval [CI] 7.1% to 13.9%), while 101 women tested positive on the blood test (prevalence: 33.7%; 95% CI 28.6% to 39.4%). Fourteen of the 15 women (93.3%) with positive results according to the modified Baermann technique, and 14 of the 23 women (56.5%) with positive charcoal cultures also had positive serological results. Serology showed a sensitivity of 63.3% and a negative predictive value of 94.4%.<br />Conclusion: In Iquitos, pregnant women have a high prevalence of S stercoralis . S. stercoralis ELISA could be an excellent tool for population-based screening, as it has a high negative predictive value that can help to rule out the presence of active infection.
Details
- Language :
- English
- ISSN :
- 2076-0817
- Volume :
- 9
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pathogens (Basel, Switzerland)
- Publication Type :
- Academic Journal
- Accession number :
- 32375325
- Full Text :
- https://doi.org/10.3390/pathogens9050348