Back to Search
Start Over
Comparison of Transatlantic Approaches to Lipid Management: The AHA/ACC/Multisociety Guidelines vs the ESC/EAS Guidelines.
- Source :
-
Mayo Clinic proceedings [Mayo Clin Proc] 2020 May; Vol. 95 (5), pp. 998-1014. - Publication Year :
- 2020
-
Abstract
- The 2018 American Heart Association/American College of Cardiology/Multisociety (AHA/ACC) guidelines and the 2019 European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines on lipid management were published less than a year apart. Both guidelines focus on reducing cardiovascular risk, but they follow different approaches in terms of methods of risk estimation, definitions of at-risk groups, and treatment goals to achieve this common underlying objective. Both recommend achieving risk-based percentage reductions of low-density lipoprotein cholesterol (LDL-C) levels with statin therapy. The ESC/EAS guidelines additionally recommend target LDL-C levels and are more liberal in supporting the use of both statin and nonstatin therapies across broader patient groups. The AHA/ACC guidelines may be considered more conservative, reserving the addition of nonstatins to maximally tolerated statins for only select patient groups based on specific LDL-C thresholds. One of the main reasons for these differences is incorporation of cost value considerations by the AHA/ACC guidelines, whereas the ESC/EAS guidelines consider an ideal setting with unlimited resources while making recommendations. In this review, we discuss similarities and differences between the 2 lipid guidelines to help clinicians become more cognizant of these recommendations and provide the best individualized patient care.<br /> (Copyright © 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Cardiovascular Diseases etiology
Cardiovascular Diseases prevention & control
Europe
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Hyperlipidemias complications
Internationality
Risk Factors
Risk Reduction Behavior
Societies, Medical
United States
Hyperlipidemias therapy
Practice Guidelines as Topic
Subjects
Details
- Language :
- English
- ISSN :
- 1942-5546
- Volume :
- 95
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Mayo Clinic proceedings
- Publication Type :
- Academic Journal
- Accession number :
- 32370858
- Full Text :
- https://doi.org/10.1016/j.mayocp.2020.01.011