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Stevens-Johnson Syndrome and Herpes Simplex Type 1 Infection during Adalimumab Therapy for Crohn's Disease.
- Source :
-
Case reports in gastrointestinal medicine [Case Rep Gastrointest Med] 2020 Apr 15; Vol. 2020, pp. 3875024. Date of Electronic Publication: 2020 Apr 15 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Stevens-Johnson syndrome (SJS) is a severe mucocutaneous adverse drug reaction with a relatively high mortality rate. SJS is described during herpes simplex virus type 1 (HSV1) infection and, rarely, even during adalimumab therapy. We report the case of a patient with Crohn's disease who developed SJS during an HSV1 infection and a contemporaneous anti-TNF α therapy with adalimumab. Remission was achieved with suspension of adalimumab and high doses of intravenous steroids and antivirals. Patients with HSV1 infection and on adalimumab therapy have a combined risk of SJS and should be monitored closely.<br />Competing Interests: The authors declare that they have no conflicts of interest.<br /> (Copyright © 2020 Jenny Roselli et al.)
Details
- Language :
- English
- ISSN :
- 2090-6528
- Volume :
- 2020
- Database :
- MEDLINE
- Journal :
- Case reports in gastrointestinal medicine
- Publication Type :
- Report
- Accession number :
- 32351742
- Full Text :
- https://doi.org/10.1155/2020/3875024