Back to Search
Start Over
Spontaneous porto-systemic shunts in liver cirrhosis: Clinical and therapeutical aspects.
- Source :
-
World journal of gastroenterology [World J Gastroenterol] 2020 Apr 21; Vol. 26 (15), pp. 1726-1732. Date of Electronic Publication: 2020 Apr 14. - Publication Year :
- 2020
-
Abstract
- Spontaneous porto-systemic shunts (SPSS) are frequent in liver cirrhosis and their prevalence increases as liver function deteriorates, probably as a consequence of worsening portal hypertension, but without achieving an effective protection against cirrhosis' complications. Several types of SPSS have been described in the literature, each one associated with different clinical manifestations. In particular, recurrent or persistent hepatic encephalopathy is more frequent in patients with splenorenal shunt, while the presence of gastric varices and consequently the incidence of variceal bleeding is more common in gastrorenal shunt. In the advanced stage, the presence of large SPSS can lead to the so called "portosystemic shunt syndrome", characterized by a progressive deterioration of hepatic function, hepatic encephalopathy and, sometimes, portal vein thrombosis. The detection of SPSS in patients with liver cirrhosis is recommended in order to prevent or treat recurrent hepatic encephalopathy or variceal bleeding.<br />Competing Interests: Conflict-of-interest statement: All authors have nothing to disclose and no conflict of interest.<br /> (©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.)
- Subjects :
- Esophageal and Gastric Varices epidemiology
Esophageal and Gastric Varices etiology
Esophageal and Gastric Varices therapy
Gastrointestinal Hemorrhage epidemiology
Gastrointestinal Hemorrhage etiology
Gastrointestinal Hemorrhage prevention & control
Hepatic Encephalopathy epidemiology
Hepatic Encephalopathy etiology
Hepatic Encephalopathy prevention & control
Humans
Incidence
Liver blood supply
Liver physiopathology
Liver Cirrhosis diagnosis
Liver Cirrhosis physiopathology
Liver Cirrhosis therapy
Liver Function Tests
Syndrome
Treatment Outcome
Venous Thrombosis epidemiology
Venous Thrombosis etiology
Venous Thrombosis prevention & control
Collateral Circulation physiology
Esophageal and Gastric Varices diagnosis
Liver Cirrhosis complications
Portal System physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 2219-2840
- Volume :
- 26
- Issue :
- 15
- Database :
- MEDLINE
- Journal :
- World journal of gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 32351289
- Full Text :
- https://doi.org/10.3748/wjg.v26.i15.1726