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Non-Opioid Substances Acute Poisonings with Suicidal Intent in Patients with Opioid Use Disorder.
- Source :
-
Folia medica [Folia Med (Plovdiv)] 2020 Mar 31; Vol. 62 (1), pp. 117-123. - Publication Year :
- 2020
-
Abstract
- Introduction: Several epidemiological studies have evaluated the role of illicit drug use in suicide behaviour.<br />Aim: To assess patients with opioid use disorder and suicidal intent related to behavior, severity of acute poisoning and the most commonly used non-opioid substances.<br />Materials and Methods: This cross sectional study included 67 patients diagnosed with opioid use disorder. The study was conducted at the University Clinic of Toxicology in Skopje over a 5-year period (2013-2017). The following variables were examined: gender, age, duration and route of opioid administration, duration of hospitalization, and types of substances used in acute poisoning. Assessment of patients’ behavior and severity of poisoning was made by using the Suicide Behaviours Questionnaire-Revised and the Poison severity score.<br />Results: The majority of patients were male (88.1%). The mean age of patients was 30±6.1 years. The average duration of opioid use disorder was 8.5±3.9. A single poisoning was found in 62.7%, double poisoning in 25.4%, and triple poisoning in 11.9% of participants. Benzodiazepines were most commonly used by the patients (55.2%). The largest number of patients (32.8%) had minor Poison severity score (PSS), and only 17.9% had severe PSS. None of the patients had a fatal suicide attempt. 86.6% of patients had a score of ≥7 indicating a high risk of repeat suicide attempts.<br />Conclusion: Benzodiazepines were most commonly used as a single or combined substance in patients with opioid use disorder. PSS indicated that most of the participants were with minor PSS and with high risk of a repeat suicide attempt.<br /> (This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Subjects :
- Adolescent
Adult
Analgesics, Opioid therapeutic use
Buprenorphine therapeutic use
Cross-Sectional Studies
Female
Heroin Dependence drug therapy
Heroin Dependence epidemiology
Humans
Male
Methadone therapeutic use
Middle Aged
Opiate Substitution Treatment
Opioid-Related Disorders drug therapy
Republic of North Macedonia epidemiology
Substance Abuse, Intravenous
Tramadol
Young Adult
Antidepressive Agents poisoning
Antipsychotic Agents poisoning
Benzodiazepines poisoning
Caustics poisoning
Drug Overdose epidemiology
Opioid-Related Disorders epidemiology
Poisoning epidemiology
Suicide, Attempted statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1314-2143
- Volume :
- 62
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Folia medica
- Publication Type :
- Academic Journal
- Accession number :
- 32337915
- Full Text :
- https://doi.org/10.3897/folmed.62.e47789