Fatal Fulminant Legionnaires' Disease in a Patient on Maintenance Hemodialysis.

Authors :: Kawashima A
Katagiri D
Kondo I
Sakamoto E
Suzuki M
Arai Y
Sato F
Tada M
Hinoshita F
Source :: Internal medicine (Tokyo, Japan) [Intern Med] 2020 Aug 01; Vol. 59 (15), pp. 1913-1918. Date of Electronic Publication: 2020 Apr 23.
Publication Year :: 2020
Abstract: We herein report a case of fulminant Legionnaires' disease with autopsy findings in a patient on maintenance hemodialysis (HD). Chronic kidney disease is a strong risk factor for Legionnaires' disease, although there have been only a few reports in HD patients. Because most patients on HD are anuric, the use of rapid assay kits to detect antigens in urine samples for the diagnosis of Legionnaires' disease is not always feasible. We suggest the use of clinical predictive tools or the loop-mediated isothermal amplification (LAMP) method, which can be applied for anuric patients, such as those on HD, with pneumonia.