Back to Search Start Over

Synthesis of α-CF 3 -substituted E-dehydroornithine derivatives via copper(i)-catalyzed hydroamination of allenes.

Authors :
Philippova AN
Vorobyeva DV
Monnier F
Osipov SN
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2020 May 06; Vol. 18 (17), pp. 3274-3280.
Publication Year :
2020

Abstract

An efficient synthetic approach to novel α-CF3-substituted E-dehydroornithine derivatives and their phosphorus analogues has been developed via the Cu(i)-catalyzed hydroamination of trifluoromethyl-containing α-allenyl-α-aminocarboxylates and α-allenyl-α-aminophosphonates with primary and secondary amines.

Details

Language :
English
ISSN :
1477-0539
Volume :
18
Issue :
17
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
32307483
Full Text :
https://doi.org/10.1039/d0ob00580k