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Liposome-bound cyclosporine: clearance after intravitreal injection.
- Source :
-
International ophthalmology [Int Ophthalmol] 1988; Vol. 12 (2), pp. 109-12. - Publication Year :
- 1988
-
Abstract
- The concentration of cyclosporine in the vitreous after intravitreal injection of 100 micrograms of either free or liposome-bound cyclosporine was studied in albino rabbits. We found that the half-life of free cyclosporine was about 6 hours and that of liposome-bound cyclosporine was about 3 days. The finding indicates that liposome-bound cyclosporine prolongs the availability of the drug.
Details
- Language :
- English
- ISSN :
- 0165-5701
- Volume :
- 12
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- International ophthalmology
- Publication Type :
- Academic Journal
- Accession number :
- 3229899
- Full Text :
- https://doi.org/10.1007/BF00137135