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Comparing Medium-Term Clinical Outcomes following XEN® 45 and XEN® 63 Device Implantation.

Authors :
Fernández-García A
Zhou Y
García-Alonso M
Andrango HD
Poyales F
Garzón N
Source :
Journal of ophthalmology [J Ophthalmol] 2020 Mar 23; Vol. 2020, pp. 4796548. Date of Electronic Publication: 2020 Mar 23 (Print Publication: 2020).
Publication Year :
2020

Abstract

Purpose: To evaluate medium-term clinical outcomes with XEN® 45 or XEN® 63 Gel Stent (Allergan, Dublin, Ireland) for treatment of primary open angle glaucoma (POAG). Materials and Methods . Retrospective, descriptive, and observational study involving 40 patients implanted with a XEN® 45 Gel Stent and 34 implanted with a XEN® 63 Gel Stent who had undergone POAG surgery and had been followed up and controlled between 12 and 36 months.<br />Results: IOP dropped from 18.02 ± 5.23 mmHg preop to 13.81 ± 1.88, 14.80 ± 2.23, and 14.62 ± 1.90 at 1, 2, and 3 years after surgery ( p < 0.001) consecutively with XEN® 45 and from 19.00 ± 6.11 mmHg preop to 15.47 ± 2.45, 14.66 ± 2.45, and 15.46 ± 2.48 at 1, 2, and 3 years after surgery ( p < 0.001) with XEN® 63. The number of drugs used by patients to treat their glaucoma decreased after undergoing surgery in both groups. Within the XEN® 45 group, mean changes at 1 year, 2 years, and 3 years amounted to 70%, 74.3%, and 37.5%, respectively, whereas within the XEN® 63 group, the mean reduction was 75%, 79.8%, and 71.9%. When comparing the outcomes for two groups, the differences did not prove to be statistically significant. More than 90% of the procedures included in the study (using either gel-stent device) were completed without any noteworthy complications.<br />Conclusion: POAG surgical procedures with either XEN® 45 or XEN® 63 Gel Stent implantation could be a safe and effective treatment approach.<br />Competing Interests: The authors declare that they have no conflicts of interest.<br /> (Copyright © 2020 Aitor Fernández-García et al.)

Details

Language :
English
ISSN :
2090-004X
Volume :
2020
Database :
MEDLINE
Journal :
Journal of ophthalmology
Publication Type :
Academic Journal
Accession number :
32280523
Full Text :
https://doi.org/10.1155/2020/4796548