Integration of denosumab therapy in the management of giant cell tumors of bone.

Authors :: Miles DT
Voskuil RT
Dale W
Mayerson JL
Scharschmidt TJ
Source :: Journal of orthopaedics [J Orthop] 2020 Mar 28; Vol. 22, pp. 38-47. Date of Electronic Publication: 2020 Mar 28 (Print Publication: 2020).
Publication Year :: 2020
Abstract: A review of the literature indicated denosumab is gaining favorability in the oncology community, particularly with increasing frequency in GCTB. Will denosumab be the breakthrough GCTB treatment? Here, we provide a pertinent case example, a review of the literature regarding the history and basic science behind the use of denosumab for GCTB, highlight the newest insights into the dosing and duration of treatment, and note advancements in the field.<br /> (© 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.)

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