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Hematological complications under hyper conditions of glucose and distilled water.
- Source :
-
Pakistan journal of pharmaceutical sciences [Pak J Pharm Sci] 2020 Mar; Vol. 33 (2), pp. 589-595. - Publication Year :
- 2020
-
Abstract
- This work presents a pilot method of hematological diagnosis about changes in: shape, size and rouleaux formation, cell count of leucocytes and platelet cells in the presence of different glucose [C <subscript>6</subscript> H <subscript>12</subscript> O <subscript>6</subscript> ] and water [H2O] concentrations. The 2D microscopic images after addition of ten different glucose concentrations to normal blood (0 mM- 450 mM) revealed the lyses (disintegration) of white blood cells (WBCs). This work provides a baseline to diagnose blood disorders and complications at labs and clinical environment.
- Subjects :
- Blood Platelets metabolism
Blood Platelets pathology
Cell Shape physiology
Distillation
Dose-Response Relationship, Drug
Glucose Solution, Hypertonic administration & dosage
Humans
Hyperglycemia blood
Hyperglycemia chemically induced
Leukocytes metabolism
Leukocytes pathology
Male
Water administration & dosage
Blood Platelets drug effects
Cell Shape drug effects
Glucose Solution, Hypertonic toxicity
Leukocytes drug effects
Water adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1011-601X
- Volume :
- 33
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Pakistan journal of pharmaceutical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 32276902