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Imaging Assessment of Complications from Transplantation from Pediatric to Adult Patients: Part 2: Hematopoietic Stem Cell Transplantation.

Authors :
Concepcion NDP
Romberg EK
Phillips GS
Lee EY
Laya BF
Source :
Radiologic clinics of North America [Radiol Clin North Am] 2020 May; Vol. 58 (3), pp. 569-582. Date of Electronic Publication: 2020 Feb 26.
Publication Year :
2020

Abstract

Hematopoietic stem cell transplantation is an intravenous transfusion of pluripotent stem cells to repopulate the marrow and restore immunocompetence. However, before transplantation, the patient undergoes a conditioning regimen to eradicate the underlying disease, subsequently resulting in an immunocompromised state. Serious and some life-threatening complications involving any organ can occur. Currently, with advances in hematopoietic stem cell transplantation techniques and posttransplant management, more pediatric patients are now living longer and into their adulthood. The goal of this review article is to discuss the common neurologic, pulmonary, and abdominal complications associated with hematopoietic stem cell transplantation with emphasis on their imaging characteristics.<br />Competing Interests: Disclosure E.Y. Lee received traveling and honorarium support from the Guebert Group as an invited speaker at an international meeting (AOSPR). The other authors have nothing to disclose.<br /> (Copyright © 2019 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1557-8275
Volume :
58
Issue :
3
Database :
MEDLINE
Journal :
Radiologic clinics of North America
Publication Type :
Academic Journal
Accession number :
32276704
Full Text :
https://doi.org/10.1016/j.rcl.2019.12.006