Back to Search
Start Over
Recurrence and Mortality of Melanoma In Situ of the Trunk or Extremities: A Surveillance, Epidemiology, and End Results Analysis.
- Source :
-
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2021 Jan 01; Vol. 47 (1), pp. 1-5. - Publication Year :
- 2021
-
Abstract
- Background: Recent studies demonstrate comparable outcomes of Mohs micrographic surgery (MMS) versus local excision (LE) for melanoma in situ. These studies are limited by their focus on the head and neck.<br />Objective: The primary objective was to compare 5-year overall and melanoma-specific mortality among patients with melanoma in situ of the trunk or extremities who undergo MMS versus LE. The secondary objective was to compare 5-year local recurrence among the same cohort of patients who undergo MMS versus LE.<br />Materials and Methods: The Surveillance, Epidemiology, and End Results (SEER) database (2000-2015) was queried to identify patients who underwent MMS versus LE for melanoma in situ of the trunk, upper extremities, or lower extremities. Outcomes were 5-year recurrence, melanoma-specific mortality, and overall mortality. Multivariable regression analyses were performed.<br />Results: Thirty three thousand nine hundred eighty-three patients underwent surgical treatment (MMS 3%; LE 97%). In adjusted analyses, there was no difference in local recurrence (hazard ratio [HR] 1.00, 95% confidence interval [CI] 0.56-1.78), melanoma-specific mortality (HR 0.89, 95% CI 0.12-6.47), nor overall mortality (HR 1.10, 95% CI 0.82-1.48) between MMS versus LE.<br />Conclusion: There is no difference of 5-year local recurrence, melanoma-specific mortality, nor overall mortality associated with MMS versus LE for melanoma in situ of the trunk or extremities.<br /> (Copyright © 2020 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.)
- Subjects :
- Carcinoma in Situ surgery
Female
Humans
Male
Melanoma surgery
Middle Aged
Neoplasm Recurrence, Local
SEER Program
Skin Neoplasms surgery
Thoracic Neoplasms surgery
United States epidemiology
Carcinoma in Situ mortality
Extremities
Melanoma mortality
Mohs Surgery
Skin Neoplasms mortality
Thoracic Neoplasms mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1524-4725
- Volume :
- 47
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
- Publication Type :
- Academic Journal
- Accession number :
- 32271178
- Full Text :
- https://doi.org/10.1097/DSS.0000000000002417