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Whole genome and phylogenetic analysis of two SARS-CoV-2 strains isolated in Italy in January and February 2020: additional clues on multiple introductions and further circulation in Europe.

Authors :
Stefanelli P
Faggioni G
Lo Presti A
Fiore S
Marchi A
Benedetti E
Fabiani C
Anselmo A
Ciammaruconi A
Fortunato A
De Santis R
Fillo S
Capobianchi MR
Gismondo MR
Ciervo A
Rezza G
Castrucci MR
Lista F
Source :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2020 Apr; Vol. 25 (13).
Publication Year :
2020

Abstract

Whole genome sequences of SARS-CoV-2 obtained from two patients, a Chinese tourist visiting Rome and an Italian, were compared with sequences from Europe and elsewhere. In a phylogenetic tree, the Italian patient's sequence clustered with sequences from Germany while the tourist's sequence clustered with other European sequences. Some additional European sequences in the tree segregated outside the two clusters containing the patients' sequences. This suggests multiple SARS-CoV-2 introductions in Europe or virus evolution during circulation.

Details

Language :
English
ISSN :
1560-7917
Volume :
25
Issue :
13
Database :
MEDLINE
Journal :
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Publication Type :
Academic Journal
Accession number :
32265007
Full Text :
https://doi.org/10.2807/1560-7917.ES.2020.25.13.2000305