Back to Search
Start Over
Melioidosis In Suspected Recurrent Tuberculosis: A disease in disguise.
- Source :
-
Journal of infection in developing countries [J Infect Dev Ctries] 2020 Mar 31; Vol. 14 (3), pp. 312-316. Date of Electronic Publication: 2020 Mar 31. - Publication Year :
- 2020
-
Abstract
- Introduction: Melioidosis, caused by the soil saprophyte B. pseudomallei, is a 'neglected' infectious disease in many Asian countries. It remained undiagnosed or misdiagnosed in India for long due to a lack of awareness and facilities to diagnose the disease; however, it is slowly gaining the status of an emerging disease recently. The disease is well known as a great mimicker, as the presentations are very similar to many other tropical diseases, and more importantly, to tuberculosis .<br />Methodology: A prospective observational study was conducted from January 2016 - December 2018 to find the occurance of melioidosis  in patients with 'recurrent' tuberculosis infection in a tertiary health care hospital from southern India. All suspected cases of recurrent tuberculosis were simultaneously tested for the presence of B. pseudomallei, and basic demographics and clinical details were documented.<br />Result: Among 11,138 patients admitted with suspected tuberculosis infection, 586 (5.2%) patients were confirmed. There was recurrent Mycobacterium tuberculosis infection in 11/586 (1.8%) cases, and 7/586 (1.2%) had growth of B. pseudomallei in culture. Patients with melioidosis had either pulmonary involvement, or bone and joint infections and deep abscesses.  Uncontrolled diabetes mellitus was the major risk factor.<br />Conclusion: The study foreshadows the need for prompt and accurate microbiological diagnosis along with a high index of suspicion from the clinicians in countries which are endemic for both melioidosis and tuberculosis, thus ameliorating the irrational anti-tuberculosis treatment.<br />Competing Interests: No Conflict of Interest is declared<br /> (Copyright (c) 2020 Rahul Garg, Tushar Shaw, Kalwaje E Vandana, Rahul Magazine, Chiranjay Mukhopadhyay.)
Details
- Language :
- English
- ISSN :
- 1972-2680
- Volume :
- 14
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of infection in developing countries
- Publication Type :
- Academic Journal
- Accession number :
- 32235093
- Full Text :
- https://doi.org/10.3855/jidc.12051