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Food Additives (Hypochlorous Acid Water, Sodium Metabisulfite, and Sodium Sulfite) Strongly Affect the Chemical and Biological Properties of Vitamin B 12 in Aqueous Solution.
- Source :
-
ACS omega [ACS Omega] 2020 Mar 10; Vol. 5 (11), pp. 6207-6214. Date of Electronic Publication: 2020 Mar 10 (Print Publication: 2020). - Publication Year :
- 2020
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Abstract
- Food additives, such as hypochlorous acid water, sodium metabisulfite, and sodium sulfite, strongly affect the chemical and biological properties of vitamin B <subscript>12</subscript> (cyanocobalamin) in aqueous solution. When cyanocobalamin (10 μmol/L) was treated with these compounds, hypochlorous acid water (an effective chlorine concentration of 30 ppm) rapidly reacted with cyanocobalamin. The maximum absorptions at 361 and 550 nm completely disappeared by 1 h, and vitamin B <subscript>12</subscript> activity was lost. There were no significant changes observed in the absorption spectra of cyanocobalamin for 0.01% (w/v) sodium metabisulfite; however, a small amount of the reaction product was formed within 48 h, which was subsequently identified as sulfitocobalamin through high-performance liquid chromatography. Similar results were shown for sodium sulfite. The effects of these food additives on the vitamin B <subscript>12</subscript> content of red shrimp and beef meats were determined, revealing no significant difference in vitamin B <subscript>12</subscript> content of shrimp and beef meats with or without the treatment even in hypochlorous acid water. The results suggest that these food additives could not react with food vitamin B <subscript>12</subscript> in food, as most of this vitamin present in food is its protein-bound form rather than the free form.<br />Competing Interests: The authors declare no competing financial interest.<br /> (Copyright © 2020 American Chemical Society.)
Details
- Language :
- English
- ISSN :
- 2470-1343
- Volume :
- 5
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- ACS omega
- Publication Type :
- Academic Journal
- Accession number :
- 32226906
- Full Text :
- https://doi.org/10.1021/acsomega.0c00425