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Children with vaccination granulomas and aluminum contact allergy: Evaluation of predispositions, avoidance behavior, and quality of life.
- Source :
-
Contact dermatitis [Contact Dermatitis] 2020 Aug; Vol. 83 (2), pp. 99-107. Date of Electronic Publication: 2020 Apr 14. - Publication Year :
- 2020
-
Abstract
- Background: Aluminum contact allergy is mostly seen in children with vaccination granulomas, following immunization with aluminum-adsorbed childhood vaccines.<br />Objectives: To characterize a cohort of children with vaccination granulomas and aluminum allergy concerning early life conditions, exacerbating factors, avoidance behavior, treatments, and potential impact on quality of life.<br />Methods: A questionnaire study was conducted among 177 children aged 0 to 15 years with vaccination granulomas and aluminum allergy, and a reference group of 61 children aged 3 to 14 years with various types of dermatitis undergoing patch testing.<br />Results: All children in the granuloma group were reportedly affected by itch. Infection exacerbated the itch in 59%. Other worsening factors were eating tin-foiled/canned food (31%) and use of aluminum-containing sunscreen (46%). Many parents took precautions to avoid aluminum exposure. Children with granulomas were more likely to be nonadherent to the National Vaccination Program than the reference group (27% vs 2%, P < .001). Parents in the granuloma group reported a decreased life quality for both parents and children compared with the reference group.<br />Conclusions: Itching vaccination granulomas and aluminum allergy have a considerable negative impact on affected children and their families, causing avoidance behavior, reduced adherence to vaccination programs, and a negative effect on the overall life quality.<br /> (© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.)
- Subjects :
- Adolescent
Aluminum adverse effects
Child
Child, Preschool
Dermatitis, Allergic Contact complications
Dermatitis, Allergic Contact psychology
Female
Granuloma complications
Granuloma psychology
Humans
Infant
Male
Risk Factors
Sunscreening Agents therapeutic use
Surveys and Questionnaires
Vaccination statistics & numerical data
Vaccines adverse effects
Vaccines chemistry
Avoidance Learning
Dermatitis, Allergic Contact etiology
Granuloma etiology
Pruritus etiology
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 1600-0536
- Volume :
- 83
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Contact dermatitis
- Publication Type :
- Academic Journal
- Accession number :
- 32219858
- Full Text :
- https://doi.org/10.1111/cod.13538