Edoxaban in elderly patient with morbid obesity and atrial fibrillation: the role of plasma levels evaluation for selecting the appropriate dose.

Authors :: Russo V
Rago A
Laezza N
Di Micco P
Giannetti L
Atripaldi L
D'Onofrio A
Golino P
Nigro G
Source :: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace [Monaldi Arch Chest Dis] 2020 Mar 20; Vol. 90 (1). Date of Electronic Publication: 2020 Mar 20.
Publication Year :: 2020
Abstract: We present the case of a 80-year-old man with atrial fibrillation, morbid obesity (weight 123 kg, height 167 cm, BMI 44.1), high clearance of creatinine and pharmacological polytherapy, in which the serial determinations of edoxaban plasma levels help us to choose the appropriate dose.

Subjects :: Aged, 80 and over
Anticoagulants pharmacokinetics
Atrial Fibrillation complications
Drug Therapy, Combination
Humans
Male
Pyridines pharmacokinetics
Thiazoles pharmacokinetics
Anticoagulants administration & dosage
Atrial Fibrillation drug therapy
Obesity, Morbid complications
Pyridines administration & dosage
Thiazoles administration & dosage

Language :: English
ISSN :: 2532-5264
Volume :: 90
Issue :: 1
Database :: MEDLINE
Journal :: Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
Publication Type :: Academic Journal
Accession number :: 32204583
Full Text :: https://doi.org/10.4081/monaldi.2020.1224

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