Back to Search
Start Over
Temporal circuit of macroscale dynamic brain activity supports human consciousness.
- Source :
-
Science advances [Sci Adv] 2020 Mar 11; Vol. 6 (11), pp. eaaz0087. Date of Electronic Publication: 2020 Mar 11 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- The ongoing stream of human consciousness relies on two distinct cortical systems, the default mode network and the dorsal attention network, which alternate their activity in an anticorrelated manner. We examined how the two systems are regulated in the conscious brain and how they are disrupted when consciousness is diminished. We provide evidence for a "temporal circuit" characterized by a set of trajectories along which dynamic brain activity occurs. We demonstrate that the transitions between default mode and dorsal attention networks are embedded in this temporal circuit, in which a balanced reciprocal accessibility of brain states is characteristic of consciousness. Conversely, isolation of the default mode and dorsal attention networks from the temporal circuit is associated with unresponsiveness of diverse etiologies. These findings advance the foundational understanding of the functional role of anticorrelated systems in consciousness.<br /> (Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).)
Details
- Language :
- English
- ISSN :
- 2375-2548
- Volume :
- 6
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Science advances
- Publication Type :
- Academic Journal
- Accession number :
- 32195349
- Full Text :
- https://doi.org/10.1126/sciadv.aaz0087