Back to Search Start Over

Gut dysbiosis and multiple sclerosis.

Authors :
Noto D
Miyake S
Source :
Clinical immunology (Orlando, Fla.) [Clin Immunol] 2022 Feb; Vol. 235, pp. 108380. Date of Electronic Publication: 2020 Mar 10.
Publication Year :
2022

Abstract

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) and T cell-mediated autoimmune processes are assumed to be involved in its pathogenesis. Recently, accumulating evidence has indicated that commensal bacteria interact with the host immune system and that the alteration of commensal bacteria composition, termed dysbiosis, is associated with various autoimmune diseases including CNS autoimmune diseases. In this review, we introduce recent findings regarding the association between gut microbiota and MS and related diseases and microbiota function in an animal model of MS.<br /> (Copyright © 2020 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1521-7035
Volume :
235
Database :
MEDLINE
Journal :
Clinical immunology (Orlando, Fla.)
Publication Type :
Academic Journal
Accession number :
32169440
Full Text :
https://doi.org/10.1016/j.clim.2020.108380