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[The study of the innate and acquired cellular immunity chains indicators in the peripheral blood of patients with HIV infection.]
- Source :
-
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2020; Vol. 65 (1), pp. 24-28. - Publication Year :
- 2020
-
Abstract
- In this study was made an attempt to reveal additional laboratory markers of white blood for preliminary estimation level of HIV-infection development. Essentially such markers these are in progress without complex equipment and expensive reagent. It was studied alterations of basic values cells of innate and acquired immunity of peripheral blood HIV-infected individuals with and without antiretroviral treatment (ART) during infection. It was estimate value leukocytes, neutrophils, monocytes, lymhpocytes, T-lymhpocytes, CD <subscript>4</subscript> <superscript>+</superscript> , CD <subscript>8</subscript> <superscript>+</superscript> T-cells, CD <subscript>4</subscript> /CD <subscript>8</subscript> index. It was used the first analysis in the time of registration for regular medical check-up and the intermediate derived during 2017-2018 years. Patients without ART and with ART before and after treatment had rates of leukocytes, lymhpocytes, T-lymhpocytes, monocytes and neutrophils within the normal guideline. Essential changes were observed in basic conventional laboratory parameters evaluation of HIV-infection dynamic (parameters of CD <subscript>4</subscript> <superscript>+</superscript> , CD <subscript>8</subscript> <superscript>+</superscript> T-cells, CD <subscript>4</subscript> /CD <subscript>8</subscript> index). Thereby it was impossible to reveal supplementary immunological markers of HIVinfection.<br />Competing Interests: The authors declare no conflict of interest.
Details
- Language :
- Russian
- ISSN :
- 0869-2084
- Volume :
- 65
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Klinicheskaia laboratornaia diagnostika
- Publication Type :
- Academic Journal
- Accession number :
- 32155003
- Full Text :
- https://doi.org/10.18821/0869-2084-2020-65-1-24-28