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The Influence of Environmental Cues on the Development of Trypanosoma cruzi in Triatominae Vector.
- Source :
-
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2020 Feb 21; Vol. 10, pp. 27. Date of Electronic Publication: 2020 Feb 21 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Trypanosoma cruzi , a hemoflagellate parasite, is the etiological agent of Chagas disease that affects about 6-7 million people worldwide, mostly in Latin America. The parasite life cycle is complex and alternates between an invertebrate host-Triatominae vector-and a mammalian host. The parasite adaptation to the several microenvironments through which it transits is critical to success in establishing infection. Moreover, environmental cues also play an important role on the parasite development, and it can modulate the infection. In the present study, we discussed how the temperature oscillations and the nutritional state of the invertebrate host can affect the parasite development, multiplication, and the differentiation process of epimastigote forms into metacyclic trypomastigotes, called metacyclogenesis. The impact of oxidative imbalance and osmotic stresses on the parasite-vector relationship are also discussed.<br /> (Copyright © 2020 Melo, Guarneri and Silber.)
- Subjects :
- Animals
Cues
Humans
Latin America
Chagas Disease
Triatominae
Trypanosoma cruzi
Subjects
Details
- Language :
- English
- ISSN :
- 2235-2988
- Volume :
- 10
- Database :
- MEDLINE
- Journal :
- Frontiers in cellular and infection microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 32154185
- Full Text :
- https://doi.org/10.3389/fcimb.2020.00027