Integration of Whole-Genome Sequencing With Circulating Tumor DNA Analysis Captures Clonal Evolution and Tumor Heterogeneity in Non-V600 BRAF Mutant Colorectal Cancer.

Subjects

Subjects :

Adult
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Biomarkers, Tumor blood
Biopsy
Circulating Tumor DNA blood
Clonal Evolution
Colorectal Neoplasms blood
Colorectal Neoplasms drug therapy
Colorectal Neoplasms pathology
ErbB Receptors antagonists & inhibitors
Genetic Heterogeneity
Humans
Liver pathology
Liver Neoplasms diagnosis
Liver Neoplasms drug therapy
Liver Neoplasms secondary
Male
Mutation
Whole Genome Sequencing
Biomarkers, Tumor genetics
Circulating Tumor DNA genetics
Colorectal Neoplasms genetics
Liver Neoplasms genetics
Proto-Oncogene Proteins B-raf genetics

Details

Language :

English

ISSN :

1938-0674

Volume :

19

Issue :

2

Database :

MEDLINE

Journal :

Clinical colorectal cancer

Publication Type :

Academic Journal

Accession number :

32151517

Full Text :

https://doi.org/10.1016/j.clcc.2020.02.001