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D-Glucuronic Acid-Coated Ultrasmall Bi₂O₃ Nanoparticles for CT Imaging.
- Source :
-
Journal of nanoscience and nanotechnology [J Nanosci Nanotechnol] 2020 Aug 01; Vol. 20 (8), pp. 4638-4642. - Publication Year :
- 2020
-
Abstract
- Ultrasmall Bi₂O₃ nanoparticles ( d <subscript>avg</subscript> = 1.5 nm) coated with biocompatible and hydrophilic D-glucuronic acid were prepared for the first time through a simple one-step polyol process and their potential as CT contrast agents were investigated by measuring their X-ray attenuation properties. Their observed X-ray attenuation power was stronger than that of a commercial iodine CT contrast agent at the same atomic concentration, as consistent with the magnitudes of atomic X-ray attenuation coefficients (i.e., Bi > I), and much stronger at the same number density. The results indicate that the nanoparticle sample is a potential CT contrast agent.
- Subjects :
- Contrast Media
Glucuronic Acid
Tomography, X-Ray Computed
Iodine
Nanoparticles
Subjects
Details
- Language :
- English
- ISSN :
- 1533-4899
- Volume :
- 20
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of nanoscience and nanotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 32126632
- Full Text :
- https://doi.org/10.1166/jnn.2020.17817