Comparison of Commensal and Clinical Isolates for Diversity of Plasmids in Escherichia coli and Klebsiella pneumoniae.

Authors :: Rodríguez-Navarro J
Miró E
Brown-Jaque M
Hurtado JC
Moreno A
Muniesa M
González-López JJ
Vila J
Espinal P
Navarro F
Source :: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Apr 21; Vol. 64 (5). Date of Electronic Publication: 2020 Apr 21 (Print Publication: 2020).
Publication Year :: 2020
Abstract: In this study, the plasmid content of clinical and commensal strains was analyzed and compared. The replicon profile was similar in both populations, except for L, M, A/C, and N (detected only in clinical strains) and HI1 (only in commensal strains). Although I1 and F were the most frequent replicons, only IncI1, sequence type 12 (ST12) was associated with bla <subscript>CMY-2</subscript> in both populations. In contrast, the widespread resistant IncF plasmids were not linked to a single epidemic plasmid.<br /> (Copyright © 2020 American Society for Microbiology.)

Subjects :: Escherichia coli isolation & purification
Feces microbiology
Humans
Klebsiella pneumoniae isolation & purification
Multilocus Sequence Typing
Bacterial Proteins genetics
Drug Resistance, Bacterial genetics
Escherichia coli genetics
Klebsiella pneumoniae genetics
Plasmids genetics
beta-Lactamases genetics

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