Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids.

Authors :: Lacomb JF
Plenker D
Tiriac H
Bucobo JC
D'souza LS
Khokhar AS
Patel H
Channer B
Joseph D
Wu M
Tuveson DA
Li E
Buscaglia JM
Source :: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association [Clin Gastroenterol Hepatol] 2021 Apr; Vol. 19 (4), pp. 845-847. Date of Electronic Publication: 2020 Feb 29.
Publication Year :: 2021
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has one of the poorest prognoses of all malignancies, with a 5-year survival rate <8%. <superscript>1</superscript> <superscript>,</superscript> <superscript>2</superscript> Suspicious lesions are typically diagnosed via endoscopic ultrasound-guided fine-needle aspiration or endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB). <superscript>3</superscript> Fewer needle passes decreases the risk of postprocedure complications, including pancreatitis and hemorrhage, while allowing additional needle passes to be used for adjuvant tissue testing, such as organoid creation and DNA sequencing.<br /> (Copyright © 2021 AGA Institute. Published by Elsevier Inc. All rights reserved.)

Subjects :: Humans
Organoids
Adenocarcinoma diagnosis
Endoscopic Ultrasound-Guided Fine Needle Aspiration methods
Pancreatic Neoplasms diagnosis

Language :: English
ISSN :: 1542-7714
Volume :: 19
Issue :: 4
Database :: MEDLINE
Journal :: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Publication Type :: Academic Journal
Accession number :: 32119924
Full Text :: https://doi.org/10.1016/j.cgh.2020.02.045

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