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Antibiotic Susceptibility of Bacterial Agents Causing Meningitis in Children Older than 1 Month.
- Source :
-
Drug research [Drug Res (Stuttg)] 2020 Apr; Vol. 70 (4), pp. 174-177. Date of Electronic Publication: 2020 Feb 28. - Publication Year :
- 2020
-
Abstract
- The frequency and antibiotic susceptibility of bacterial meningitis in children older than one month at Children's Medical Center during 2012-2017 were evaluated in this study. The CSF samples were cultured, and antibiotic sensitivity tests were performed. The samples were cultured on chocolate agar, blood agar (for gram positive) and Mkanky (for gram negative). The antimicrobial susceptibility of the isolates was determined using the disc diffusion method. In total, 72 samples were positive for bacterial infection where Staphylococcus epidermidis (20.8%) was seen most and Enterobacter (1.4%) and Pseudomonas aeruginosa (1.4%) was seen least. Most of these patients were under 1 year of the age and overall frequency of positive cultures of CSF in men (58.3%) was greater than women (41.7%). Bacterial meningitis has relatively diverse etiological factors that include; time of infection, geographical location and age. Most commonly seen bacteria were Staphylococcus aureus with S.epidermidis whereas, Escherichia coli and Pseudomonas aeruginosa was seen least. This result can be substantial in hospitalized patients, because these bacteria are also the result of nosocomial infections.<br />Competing Interests: The other authors have no conflicts of interest to disclose.<br /> (© Georg Thieme Verlag KG Stuttgart · New York.)
- Subjects :
- Anti-Bacterial Agents therapeutic use
Child, Preschool
Drug Resistance, Bacterial
Enterobacter drug effects
Enterobacter isolation & purification
Escherichia coli drug effects
Escherichia coli isolation & purification
Female
Humans
Infant
Iran
Male
Microbial Sensitivity Tests
Pseudomonas aeruginosa drug effects
Pseudomonas aeruginosa isolation & purification
Retrospective Studies
Sex Factors
Staphylococcus aureus drug effects
Staphylococcus aureus isolation & purification
Staphylococcus epidermidis drug effects
Staphylococcus epidermidis isolation & purification
Anti-Bacterial Agents pharmacology
Meningitis, Bacterial drug therapy
Meningitis, Bacterial microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 2194-9387
- Volume :
- 70
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Drug research
- Publication Type :
- Academic Journal
- Accession number :
- 32110818
- Full Text :
- https://doi.org/10.1055/a-1112-7006