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[Research progress of kisspeptin in female reproductive endocrine and assisted reproductive techniques].
- Source :
-
Sheng li xue bao : [Acta physiologica Sinica] [Sheng Li Xue Bao] 2020 Feb 25; Vol. 72 (1), pp. 125-132. - Publication Year :
- 2020
-
Abstract
- In recent years, it has been found that kisspeptin plays some key roles in the physiological processes of the brain, such as gender differentiation, positive and negative feedback of sex hormones, onset of puberty, and transduction of energy signals in the body, which suggests that kisspeptin may be a key molecule for the maturation and regulation of female reproductive function. In addition to the systemic roles of the kisspeptin, its local roles in reproductive organs are constantly being discovered. With the discovery that kisspeptin is involved in the pathological process of reproductive endocrine diseases such as isolated hypogonadotropic hypogonadism (IHH), polycystic ovary syndrome (PCOS), premature ovarian failure (POF) and pathological hyperprolactinemia, exogenous application of kisspeptin to solve reproductive problems has become a new hot topic. The review focuses on the research progress of kisspeptin in the female reproductive system, especially on its application in assisted reproduction.
- Subjects :
- Female
Gonadal Steroid Hormones physiology
Humans
Hyperprolactinemia physiopathology
Hypogonadism physiopathology
Kisspeptins pharmacology
Polycystic Ovary Syndrome physiopathology
Pregnancy
Primary Ovarian Insufficiency physiopathology
Kisspeptins physiology
Reproductive Techniques, Assisted
Subjects
Details
- Language :
- Chinese
- ISSN :
- 0371-0874
- Volume :
- 72
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Sheng li xue bao : [Acta physiologica Sinica]
- Publication Type :
- Academic Journal
- Accession number :
- 32099990