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Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV.
- Source :
-
Viruses [Viruses] 2020 Feb 22; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 22. - Publication Year :
- 2020
-
Abstract
- After the outbreak of the severe acute respiratory syndrome (SARS) in the world in 2003, human coronaviruses (HCoVs) have been reported as pathogens that cause severe symptoms in respiratory tract infections. Recently, a new emerged HCoV isolated from the respiratory epithelium of unexplained pneumonia patients in the Wuhan seafood market caused a major disease outbreak and has been named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus causes acute lung symptoms, leading to a condition that has been named as "coronavirus disease 2019" (COVID-19). The emergence of SARS-CoV-2 and of SARS-CoV caused widespread fear and concern and has threatened global health security. There are some similarities and differences in the epidemiology and clinical features between these two viruses and diseases that are caused by these viruses. The goal of this work is to systematically review and compare between SARS-CoV and SARS-CoV-2 in the context of their virus incubation, originations, diagnosis and treatment methods, genomic and proteomic sequences, and pathogenic mechanisms.<br />Competing Interests: The authors declare no conflict of interest.
- Subjects :
- Animals
COVID-19
China epidemiology
Chiroptera virology
Disease Reservoirs
Disease Susceptibility
Eutheria virology
Genome, Viral
Global Health
Humans
Infectious Disease Incubation Period
Proteome
SARS-CoV-2
Sequence Alignment
Viral Proteins
Betacoronavirus chemistry
Betacoronavirus genetics
Betacoronavirus pathogenicity
Coronavirus Infections diagnosis
Coronavirus Infections epidemiology
Coronavirus Infections therapy
Coronavirus Infections virology
Pneumonia, Viral diagnosis
Pneumonia, Viral epidemiology
Pneumonia, Viral therapy
Pneumonia, Viral virology
Severe acute respiratory syndrome-related coronavirus chemistry
Severe acute respiratory syndrome-related coronavirus genetics
Severe acute respiratory syndrome-related coronavirus pathogenicity
Severe Acute Respiratory Syndrome diagnosis
Severe Acute Respiratory Syndrome epidemiology
Severe Acute Respiratory Syndrome therapy
Severe Acute Respiratory Syndrome virology
Subjects
Details
- Language :
- English
- ISSN :
- 1999-4915
- Volume :
- 12
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Viruses
- Publication Type :
- Academic Journal
- Accession number :
- 32098422
- Full Text :
- https://doi.org/10.3390/v12020244