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Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV.

Authors :
Xu J
Zhao S
Teng T
Abdalla AE
Zhu W
Xie L
Wang Y
Guo X
Source :
Viruses [Viruses] 2020 Feb 22; Vol. 12 (2). Date of Electronic Publication: 2020 Feb 22.
Publication Year :
2020

Abstract

After the outbreak of the severe acute respiratory syndrome (SARS) in the world in 2003, human coronaviruses (HCoVs) have been reported as pathogens that cause severe symptoms in respiratory tract infections. Recently, a new emerged HCoV isolated from the respiratory epithelium of unexplained pneumonia patients in the Wuhan seafood market caused a major disease outbreak and has been named the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This virus causes acute lung symptoms, leading to a condition that has been named as "coronavirus disease 2019" (COVID-19). The emergence of SARS-CoV-2 and of SARS-CoV caused widespread fear and concern and has threatened global health security. There are some similarities and differences in the epidemiology and clinical features between these two viruses and diseases that are caused by these viruses. The goal of this work is to systematically review and compare between SARS-CoV and SARS-CoV-2 in the context of their virus incubation, originations, diagnosis and treatment methods, genomic and proteomic sequences, and pathogenic mechanisms.<br />Competing Interests: The authors declare no conflict of interest.

Details

Language :
English
ISSN :
1999-4915
Volume :
12
Issue :
2
Database :
MEDLINE
Journal :
Viruses
Publication Type :
Academic Journal
Accession number :
32098422
Full Text :
https://doi.org/10.3390/v12020244