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Risk Factors for Complicated Lymphadenitis Caused by Nontuberculous Mycobacteria in Children.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2020 Mar; Vol. 26 (3), pp. 579-586. - Publication Year :
- 2020
-
Abstract
- Nontuberculous mycobacteria (NTM) are an emerging cause of infections, including chronic lymphadenitis in children. To identify risk factors for NTM lymphadenitis, particularly complicated disease, we collected epidemiologic, clinical, and microbiological data on 138 cases of NTM lymphadenitis in children across 13 centers in Germany and Austria. We assessed lifestyle factors but did not identify specific risk behaviors. We noted that more cases of NTM lymphadenitis occurred during cold months than during warm months. Moreover, we noted female sex and age <5.5 years as potential risk factors. Complete extirpation of the affected lymph node appeared to be the best therapeutic measure. We integrated the study data to develop a simple risk score to predict unfavorable clinical outcomes for NTM lymphadenitis.
- Subjects :
- Adolescent
Age Factors
Austria epidemiology
Child
Child, Preschool
Female
Germany epidemiology
Humans
Infant
Infant, Newborn
Lymphadenitis microbiology
Male
Mycobacterium Infections, Nontuberculous microbiology
Registries
Retrospective Studies
Risk Factors
Seasons
Sex Factors
Lymphadenitis epidemiology
Mycobacterium Infections, Nontuberculous epidemiology
Nontuberculous Mycobacteria isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 26
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 32091372
- Full Text :
- https://doi.org/10.3201/eid2603.191388