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Improvement in arterial stiffness (pOpmètre®) after bariatric surgery. Results from a prospective study.
- Source :
-
Annales d'endocrinologie [Ann Endocrinol (Paris)] 2020 Feb; Vol. 81 (1), pp. 44-50. Date of Electronic Publication: 2020 Feb 01. - Publication Year :
- 2020
-
Abstract
- Background: Arterial stiffness (AS) is an independent predictor of cardiovascular risk, and could be used as a surrogate marker of improvement in cardiovascular risk following bariatric surgery. The aim of this study was to compare AS before and after surgery.<br />Methods: One hundred and thirty-four patients undergoing bariatric surgery between May 2016 and January 2019 were prospectively included. AS was measured on pulse wave velocity (PWV) with the pOpmètre® device pre- and postoperatively. The main endpoint was change in PWV between baseline and 3 months post-surgery.<br />Results: Overall, mean PWV was 6.87m/s preoperatively and 6.71m/s at 3 months (P=0.7148). Patients with pathologic PWV (>2 standard deviations from expected value for age) showed significant improvement at 3 months (31 patients; 10.1m/s preoperatively vs 7.5m/s at 3 months; P=0.007). These results did not correlate with improvement in other clinical or biological parameters following surgery (excess weight loss, mean blood pressure, fasting blood glucose, waist circumference, body composition).<br />Conclusion: These results suggest that pathological arterial stiffness may resolve following bariatric surgery independently of the other factors influencing cardiovascular risk in obesity.<br /> (Copyright © 2020 Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Adolescent
Adult
Aged
Cardiovascular Diseases epidemiology
Cardiovascular Diseases etiology
Cardiovascular Diseases physiopathology
Female
Follow-Up Studies
Humans
Male
Middle Aged
Obesity, Morbid epidemiology
Postoperative Period
Prospective Studies
Risk Factors
Young Adult
Bariatric Surgery rehabilitation
Obesity, Morbid physiopathology
Obesity, Morbid surgery
Vascular Stiffness physiology
Subjects
Details
- Language :
- English
- ISSN :
- 2213-3941
- Volume :
- 81
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annales d'endocrinologie
- Publication Type :
- Academic Journal
- Accession number :
- 32081364
- Full Text :
- https://doi.org/10.1016/j.ando.2020.01.002