Randomized phase 1 study of sequential ("primed") vs. concurrent decitabine in combination with cladribine, cytarabine, G-CSF, and mitoxantrone (CLAG-M) in adults with newly diagnosed or relapsed/refractory acute myeloid leukemia (AML) or other high-grade myeloid neoplasm.

Authors :: Palmieri R
Buckley SA
Othus M
Halpern AB
Percival MM
Scott BL
Hendrie PC
Becker PS
Oehler VG
Estey EH
Walter RB
Source :: Leukemia & lymphoma [Leuk Lymphoma] 2020 Jul; Vol. 61 (7), pp. 1728-1731. Date of Electronic Publication: 2020 Feb 20.
Publication Year :: 2020

Subjects :: Adult
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Humans
Treatment Outcome
Cladribine therapeutic use
Cytarabine therapeutic use
Decitabine therapeutic use
Granulocyte Colony-Stimulating Factor therapeutic use
Leukemia, Myeloid, Acute diagnosis
Leukemia, Myeloid, Acute drug therapy
Mitoxantrone therapeutic use

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