Back to Search
Start Over
Click-tambjamines as efficient and tunable bioactive anion transporters.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2020 Mar 12; Vol. 56 (21), pp. 3218-3221. - Publication Year :
- 2020
-
Abstract
- A novel class of transmembrane anion carriers, the click-tambjamines, display remarkable anionophoric activities in model liposomes and living cells. The versatility of this building block for the generation of molecular diversity offers promise to develop future drugs based on this design.
- Subjects :
- A549 Cells
Anions chemical synthesis
Anions chemistry
Anions pharmacology
Antineoplastic Agents chemical synthesis
Antineoplastic Agents chemistry
Cell Line
Cell Proliferation drug effects
Crystallography, X-Ray
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Humans
Ion Transport
Liposomes chemistry
MCF-7 Cells
Models, Molecular
Molecular Structure
Pyrroles chemical synthesis
Pyrroles chemistry
Structure-Activity Relationship
Antineoplastic Agents pharmacology
Pyrroles pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 56
- Issue :
- 21
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 32073062
- Full Text :
- https://doi.org/10.1039/d0cc00643b