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The Ashodaya PrEP project: Lessons and implications for scaling up PrEP from a community-led demonstration project among female sex workers in Mysore, India.
- Source :
-
Global public health [Glob Public Health] 2020 Jun; Vol. 15 (6), pp. 889-904. Date of Electronic Publication: 2020 Feb 18. - Publication Year :
- 2020
-
Abstract
- To inform PrEP roll out, Ashodaya Samithi, a sex workers' collective, conducted a community-led prospective demonstration project among female sex workers in Mysore and Mandya, India. Following a community preparedness phase and pre-screening, participants were recruited for clinical screening and enrolment, provided PrEP as part of combination HIV prevention, and followed for 16 months. Adherence was measured by self-reported pill intake and by tenofovir blood level testing among a subset of participants. Of the 647 participants enrolled, 640 completed follow-up. Condom use remained stable and no HIV seroconversions occurred. Self-reported daily PrEP intake over the last month was 97.97% at the end of the study. Tenofovir blood levels >40 ng/mL (consistent with steady state dosing) were detected among 80% ( n = 68/85) and 90.48% ( n = 76/84) of participants at month 3 and 6, respectively. Our study holds important insights for rolling out PrEP in community settings as part of targeted HIV prevention interventions.
Details
- Language :
- English
- ISSN :
- 1744-1706
- Volume :
- 15
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Global public health
- Publication Type :
- Academic Journal
- Accession number :
- 32070217
- Full Text :
- https://doi.org/10.1080/17441692.2020.1724316