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Ominous Occurrence of Spinal Intradural Primary Malignant Peripheral Nerve Sheath Tumor Four Decades following Radiation Therapy for Testicular Seminoma.
- Source :
-
Case reports in neurological medicine [Case Rep Neurol Med] 2020 Jan 27; Vol. 2020, pp. 1792582. Date of Electronic Publication: 2020 Jan 27 (Print Publication: 2020). - Publication Year :
- 2020
-
Abstract
- Primary intradural malignant peripheral nerve sheath tumor (MPNST) is an extremely rare diagnosis and is associated with an extremely poor prognosis. A 77-year-old man diagnosed with an intradural MPNST, more than 40 years after radiation for a testicular seminoma, is reported. Intradural MPNSTs of the spine outside the setting of neurofibromatosis is extremely rare and can masquerade as common benign nerve sheath tumors, on imaging. An older age at presentation with short duration of symptoms and prior regional radiation treatment encompassing the spine in the treatment field regardless of remoteness should alert the oncologists and neurosurgeons to the possible existence of this rare and aggressive tumor, as the management, and overall prognosis of this tumor is distinctly different compared to the usual intradural spinal tumors.<br />Competing Interests: The authors declare that they have no conflicts of interest.<br /> (Copyright © 2020 Osmond C. Wu et al.)
Details
- Language :
- English
- ISSN :
- 2090-6668
- Volume :
- 2020
- Database :
- MEDLINE
- Journal :
- Case reports in neurological medicine
- Publication Type :
- Report
- Accession number :
- 32047679
- Full Text :
- https://doi.org/10.1155/2020/1792582