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Interstitial Lung Abnormalities in People With HIV Infection and Uninfected Controls.
- Source :
-
The Journal of infectious diseases [J Infect Dis] 2020 Jun 11; Vol. 221 (12), pp. 1973-1977. - Publication Year :
- 2020
-
Abstract
- Background: Chest computed tomography (CT) findings in well-treated people with HIV infection (PWH) remain poorly characterized.<br />Methods: Cross-sectional analysis examining interstitial chest CT findings in PWH (n = 754) and uninfected controls (n = 470).<br />Results: HIV infection was independently associated with 1.82 (95% CI, 1.18-2.88) and 5.15 (95% CI, 1.72-22.2) higher adjusted odds of any interstitial lung abnormality and findings suspicious for interstitial lung disease, respectively.<br />Conclusions: HIV infection was independently associated with interstitial lung abnormalities and findings suspicious for interstitial lung disease. Whether these abnormalities develop into more recognizable disease states over time is unknown but warrants further investigation.<br /> (© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.)
- Subjects :
- Aged
Cross-Sectional Studies
Female
HIV Infections drug therapy
HIV Infections immunology
Humans
Lung immunology
Lung Diseases, Interstitial diagnosis
Lung Diseases, Interstitial immunology
Male
Middle Aged
Prevalence
Risk Assessment
Tomography, X-Ray Computed
Anti-HIV Agents therapeutic use
HIV Infections complications
Lung diagnostic imaging
Lung Diseases, Interstitial epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1537-6613
- Volume :
- 221
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 32002544
- Full Text :
- https://doi.org/10.1093/infdis/jiaa047