A feasible sonochemical approach to synthesize CuO@CeO 2 nanomaterial and their enhanced non-enzymatic sensor performance towards neurotransmitter.

A nanostructured and high conductive cupric oxide (CuO NPs) with hierarchical CeO ₂ sheets-like structure was synthesized by a facile sonochemical approach. Furthermore, CuO/CeO ₂ nanostructure is synthesized by high-intensity ultrasonic probe (Ti-horn, 50 kHz and 100 W) at ambient air. Moreover, the synthesized CuO/CeO ₂ material was characterized by various analytical techniques including FESEM, EDX, XRD and electrochemical methods. Then, the synthesized CuO/CeO ₂ composite was applied for the electrocatalytic detection of dopamine using CV and DPV techniques. In addition, the CuO/CeO ₂ modified electrode has good electrocatalytic performance with high linear range from 0.025 to 98.5 µM towards the determination of dopamine drug and high sensitivity of the CuO/CeO ₂ modified drug sensor was calculated as 16.34 nM and 4.823 μA·µM ^-1 ·cm ^-2 , respectively. Moreover, a repeatability, reproducibility and stability of the CuO@CeO ₂ mixture modified electrode were analyzed towards the determination of dopamine biomolecule. Interestingly, the real time application of CuO@CeO ₂ modified electrode was established in different serum and drug samples.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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