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Quinoline H 2 S donor decorated fluorescent carbon dots: visible light responsive H 2 S nanocarriers.
- Source :
-
Journal of materials chemistry. B [J Mater Chem B] 2020 Feb 07; Vol. 8 (5), pp. 1026-1032. Date of Electronic Publication: 2020 Jan 15. - Publication Year :
- 2020
-
Abstract
- Recent studies have shown that the utility of nanocarriers for the transportation of gaseous signalling molecules to their target site in a biological environment is an effective approach. In this work, we have developed for the first time visible light responsive nanocarriers for the effective release of H <subscript>2</subscript> S. Our newly developed nanocarriers for H <subscript>2</subscript> S release are constructed using two main ingredients: fluorescent carbon dots and quinoline as an H <subscript>2</subscript> S donor. The developed nanocarriers provided interesting properties like good solubility under physiological conditions, excellent fluorescence properties and efficient release ability of H <subscript>2</subscript> S with good quantum yield upon visible light irradiation. In vitro studies revealed that our designed nanocarriers exhibited abilities like efficient cellular internalization and good biocompatibility.
- Subjects :
- Biocompatible Materials chemical synthesis
Carbon chemistry
Fluorescent Dyes chemical synthesis
HeLa Cells
Humans
Materials Testing
Optical Imaging
Particle Size
Quantum Dots chemistry
Surface Properties
Biocompatible Materials chemistry
Fluorescent Dyes chemistry
Hydrogen Sulfide chemistry
Light
Nanoparticles chemistry
Quinolines chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 2050-7518
- Volume :
- 8
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of materials chemistry. B
- Publication Type :
- Academic Journal
- Accession number :
- 31939466
- Full Text :
- https://doi.org/10.1039/c9tb02157d