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[Anti-NMDAR encephalitis associated with relapsing optic neuritis: a case report and differential diagnosis].

Authors :
Belova AN
Grygorieva VN
Rasteryaeva MV
Ruina EA
Belova EM
Solovieva VS
Boyko AN
Source :
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2019; Vol. 119 (10. Vyp. 2), pp. 137-146.
Publication Year :
2019

Abstract

Autoimmune encephalitis with antibodies to NMDA receptors, or anti-NMDAR encephalitis, is the most common form of autoimmune encephalitis. The disease is curable, however, the lack of timely therapy can lead to the disability of patients or to the death. Difficulties in the diagnosis of anti-NMDAR encephalitis are caused by the heterogeneity of its manifestations, a possible overlapping with other autoimmune diseases and insufficient awareness about this form of encephalitis. This article presents the literature review and describes the case of anti-NMDAR encephalitis associated with recurrent optic neuritis, which might be an atypical manifestation for this disease. Optic neuritis could not be explained by overlapping with multiple sclerosis or neuromyelitis optica spectrum disorders.

Details

Language :
Russian
ISSN :
1997-7298
Volume :
119
Issue :
10. Vyp. 2
Database :
MEDLINE
Journal :
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Publication Type :
Academic Journal
Accession number :
31934999
Full Text :
https://doi.org/10.17116/jnevro2019119102137