Software development for hepatopulmonary shunt estimation by gamma camera method in transarterial radioembolization.

Authors :: Jha AK
Mithun S
Puranik A
Purandare NC
Shah S
Agrawal A
Kulkarni SS
Shetty N
Rangarajan V
Source :: World journal of nuclear medicine [World J Nucl Med] 2019 Dec 18; Vol. 18 (4), pp. 366-372. Date of Electronic Publication: 2019 Dec 18 (Print Publication: 2019).
Publication Year :: 2019
Abstract: Trans-arterial radioembolization (TARE) is an established treatment for inoperable hepatocellular carcinoma and liver metastases from Carcinoma of gastrointestinal tract. Radiation-induced toxicity to the lung parenchyma is the dose-limiting factor in TARE. Pretreatment hepatopulmonary shunt (HPS) is estimated by gamma camera method by transarterial administration of 370MBq <superscript>99m</superscript> Tc macro aggregated albumin. We have developed HPS software on XELERIS-1.123 workstation, GE medical systems, Milwaukee, USA, for accurate calculation of HPS. This software has also been tested on a higher version of XELERIS workstation, and it has been found to work well in all versions.<br />Competing Interests: There are no conflicts of interest.<br /> (Copyright: © 2019 World Journal of Nuclear Medicine.)

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