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Guidelines for Long-Term Follow-Up after Childhood Cancer: Practical Implications for the Daily Work.
- Source :
-
Oncology research and treatment [Oncol Res Treat] 2020; Vol. 43 (3), pp. 61-69. Date of Electronic Publication: 2020 Jan 13. - Publication Year :
- 2020
-
Abstract
- Background: Many childhood cancer survivors develop treatment-associated late effects emerging years or even decades after the end of treatment. Evidence-based guidelines recommend risk-adapted screening, facilitating early diagnosis and management of these sequelae. Long-term follow-up (LTFU) in specialized late effects clinics is devised to implement screening recommendations in the care of childhood cancer survivors.<br />Objectives: To create a practical LTFU tool for the daily practice.<br />Methods: Current guidelines and screening recommendations concerning LTFU in adult survivors of childhood cancer were reviewed and a comprehensive LTFU approach was developed.<br />Results: A risk stratification model assigning patients to three risk groups with different screening recommendations and frequencies is presented based on current LTFU guidelines. Furthermore, a model of LTFU in a clinical multidisciplinary team is proposed.<br />Conclusions: Although late morbidity and mortality in childhood cancer survivors have been attenuated in the last decade by reducing treatment toxicities, a high proportion of long-term survivors already is or will still be affected by treatment-associated chronic health conditions. With the knowledge of late effects and their occurrence as a consequence of specific treatment modalities, practical LTFU recommendations are essential to achieve standardized and structured LTFU care.<br /> (© 2020 S. Karger AG, Basel.)
Details
- Language :
- English
- ISSN :
- 2296-5262
- Volume :
- 43
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Oncology research and treatment
- Publication Type :
- Academic Journal
- Accession number :
- 31931503
- Full Text :
- https://doi.org/10.1159/000504200