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Revisiting anticipatory hedonic processing in patients with schizophrenia: An examination between representation activation and maintenance.
- Source :
-
Schizophrenia research [Schizophr Res] 2020 Feb; Vol. 216, pp. 138-146. Date of Electronic Publication: 2019 Dec 24. - Publication Year :
- 2020
-
Abstract
- Background: Anticipatory anhedonia is one of the key deficits found in patients with schizophrenia (SCZ). However, the underlying mechanism of this deficit remains unclear. The present study examined whether representation activation and maintenance capacity influenced anticipatory experiences in SCZ patients.<br />Methods: We recruited 46 SCZ patients (26 males) and 45 matched healthy controls (24 males). The Reward Representation Activation and Maintenance (RRAM) Task was administrated to assess anticipatory experience and representation activation and maintenance capacity.<br />Results: SCZ patients exhibited lower subjective arousal than controls in anticipation of rewards with high probability when representation activation and maintenance were difficult to accomplish. SCZ patients also tended to reduce their button presses more than HC when they were required to maintain reward representation.<br />Conclusions: Our findings suggest that representation activation and maintenance may partially account for anticipatory anhedonia observed in SCZ patients.<br />Competing Interests: Declaration of competing interest The authors reported no conflicts of interest with this work.<br /> (Copyright © 2019 Elsevier B.V. All rights reserved.)
- Subjects :
- Anhedonia
Anticipation, Psychological
Humans
Male
Motivation
Reward
Schizophrenia
Subjects
Details
- Language :
- English
- ISSN :
- 1573-2509
- Volume :
- 216
- Database :
- MEDLINE
- Journal :
- Schizophrenia research
- Publication Type :
- Academic Journal
- Accession number :
- 31882275
- Full Text :
- https://doi.org/10.1016/j.schres.2019.12.013