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Increasing prevalence of multidrug-resistant mcr-1-positive Escherichia coli isolates from fresh vegetables and healthy food animals in South Korea.
- Source :
-
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2020 Mar; Vol. 92, pp. 53-55. Date of Electronic Publication: 2019 Dec 23. - Publication Year :
- 2020
-
Abstract
- Colistin is a last-resort antimicrobial against multidrug-resistant gram-negative bacteria. The occurrence and spread of colistin resistance in humans and animals have been reported globally. This study was performed to investigate the prevalence and antimicrobial susceptibility of mcr-harboring colistin-resistant Enterobacteriaceae from retail vegetables and food animals in South Korea in 2018. The mcr-1 gene was detected in Escherichia coli isolates from 0.076% (1/1324) of vegetables, 5.9% (2/34) of chickens, 6.8% (4/59) of pigs, and 0% (0/57) of cattle. Other mcr genes were not detected. All seven of the mcr-1-positive isolates showed multidrug resistance and co-produced β-lactamases. Multilocus sequence typing analysis revealed five known E. coli sequence types (STs), including ST10 in the vegetable sample. The study findings demonstrated that the mcr-1 gene has emerged in vegetables and is increasingly detected in food animals in South Korea, highlighting the importance of continuous monitoring and control of colistin-resistant Enterobacteriaceae to prevent them from being transmitted to humans.<br /> (Copyright © 2019 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
- Subjects :
- Animals
Anti-Bacterial Agents pharmacology
Cattle
Chickens
Drug Resistance, Bacterial genetics
Escherichia coli drug effects
Escherichia coli metabolism
Escherichia coli Proteins genetics
Humans
Multilocus Sequence Typing
Prevalence
Republic of Korea
Swine
beta-Lactamases metabolism
Colistin pharmacology
Escherichia coli isolation & purification
Escherichia coli Proteins biosynthesis
Food Microbiology
Vegetables microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3511
- Volume :
- 92
- Database :
- MEDLINE
- Journal :
- International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 31877351
- Full Text :
- https://doi.org/10.1016/j.ijid.2019.12.025