Exposure to Leishmania spp. infection and Lutzomyia spp. in individuals living in an area endemic for visceral leishmaniasis in Brazil.

Authors :: Hirata KY
Oliveira Sobrinho EB
Rigon L
Utsunomiya YT
Tomokane TY
Laurenti MD
Marcondes M
Source :: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2019 Dec 20; Vol. 53, pp. e20190320. Date of Electronic Publication: 2019 Dec 20 (Print Publication: 2019).
Publication Year :: 2019
Abstract: Introduction: This study aimed to investigate human exposure to Leishmania spp. infection and sandflies in an area endemic for the disease.<br />Methods: The presence of antibodies specific for Leishmania spp. and saliva of Lutzomyia spp. and that of L. infantum DNA in blood were evaluated.<br />Results: Antibodies against Leishmania spp. and sandfly saliva were observed in 20.8% and 37.7% of individuals, respectively. DNA of Leishmania spp. was amplified from the blood of one patient.<br />Conclusions: The results suggest that Leishmania spp. infection may be underdiagnosed in this area.

Subjects :: Adolescent
Adult
Aged
Animals
Brazil
Enzyme-Linked Immunosorbent Assay
Female
Humans
Leishmania genetics
Leishmania immunology
Leishmaniasis, Visceral epidemiology
Male
Middle Aged
Polymerase Chain Reaction
Young Adult
Insect Vectors parasitology
Leishmania isolation & purification
Leishmaniasis, Visceral transmission
Psychodidae parasitology

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