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BILATERAL AVASCULAR NECROSIS OF SACRAL LATERAL MASSES AFTER A COMPLETE RADIOLOGICAL RESPONSE OF LOCALLY ADVANCED RECTAL CANCER TREATED WITH NEOADJUVANT CHEMORADIATION THERAPY. CASE REPORT.
- Source :
-
Problemy radiatsiinoi medytsyny ta radiobiolohii [Probl Radiac Med Radiobiol] 2019 Dec; Vol. 24, pp. 537-551. - Publication Year :
- 2019
-
Abstract
- We present a rare case report of a bilateral avascular necrosis of lateral sacral masses in a patient who developed a sustainable complete clinical and radiological response after chemoradiotherapy for locally advanced rectal cancer. It is shown that despite the standardized and precise planning and fractioning for neoadjuvant chemoradiation therapy for locally advanced rectal cancer, the biological effects of ionizing radiation on critical organs can be va- ried both in time of occurrence and in structure. Evaluating the effect of neoadjuvant chemoradiation therapy, one should take into account the possibility of the development of even very rare effects of ionizing radiation on criti- cal organs and include their early detection in the diagnostic algorithm.<br /> (V. V. Zvirych, D. E. Makhmudov, M. I. Paliiy, A. V. Ashykhmin, O. O. Kolesnik.)
- Subjects :
- Adenocarcinoma diagnostic imaging
Adenocarcinoma pathology
Aged
Antineoplastic Agents therapeutic use
Humans
Magnetic Resonance Imaging
Male
Necrosis diagnostic imaging
Necrosis pathology
Neoplasm Recurrence, Local diagnostic imaging
Neoplasm Recurrence, Local pathology
Radiation, Ionizing
Rectal Neoplasms diagnostic imaging
Rectal Neoplasms pathology
Rectum diagnostic imaging
Rectum drug effects
Rectum pathology
Rectum radiation effects
Remission Induction
Sacrum diagnostic imaging
Sacrum drug effects
Sacrum pathology
Sacrum radiation effects
Treatment Outcome
Adenocarcinoma therapy
Chemoradiotherapy methods
Necrosis therapy
Neoadjuvant Therapy methods
Neoplasm Recurrence, Local therapy
Rectal Neoplasms therapy
Subjects
Details
- Language :
- English; Ukrainian
- ISSN :
- 2313-4607
- Volume :
- 24
- Database :
- MEDLINE
- Journal :
- Problemy radiatsiinoi medytsyny ta radiobiolohii
- Publication Type :
- Academic Journal
- Accession number :
- 31841494
- Full Text :
- https://doi.org/10.33145/2304-8336-2019-24-537-551