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[Sebotropic drug eruption after ingestion of bee pollen].
- Source :
-
Annales de dermatologie et de venereologie [Ann Dermatol Venereol] 2020 Feb; Vol. 147 (2), pp. 135-139. Date of Electronic Publication: 2019 Dec 09. - Publication Year :
- 2020
-
Abstract
- Introduction: The medical literature contains five cases of exanthema with sebaceous tropism induced by consumption of kava-kava extract filed under the name of sebotropic drug reaction. Herein we report a new case following consumption of bee pollen.<br />Patients and Methods: A 37-year-old man consulted for erythemato-papular and fixed plaques of the face, upper trunk and shoulders present for 3 days. Standard blood tests were normal except for neutrophil leukocytosis at 9.8 G/l and eosinophilia at 1.4 G/l. Cutaneous biopsy of a facial plaque revealed folliculocentric lesions with necrosis of sebocytes in the sebaceous gland, associated with an eosinophil-rich infiltrate. The patient had begun consuming bee-pollen granules 3 weeks before the onset of symptoms. The rash regressed within 3 weeks of cessation of pollen consumption. Patch tests (ICDRG battery, propolis 1% Vaseline dilution and bee pollen provided by the patient, both pure and in a 30% dilution in Vaseline) were negative at 48 and 72h.<br />Discussion: The clinical-pathological correlation was consistent with a diagnosis of sebotropic drug reaction induced by the consumption of bee pollen. The diagnosis was based on papular exanthema of the seborrheic zones occurring 2 to 3 weeks after initial intake of the offending substance, with histological evidence of inflammatory necrosis of the sebaceous glands.<br />Conclusion: We report what is to our knowledge the first case of sebotropic drug reaction following ingestion of bee pollen.<br /> (Copyright © 2019 Elsevier Masson SAS. All rights reserved.)
Details
- Language :
- French
- ISSN :
- 0151-9638
- Volume :
- 147
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Annales de dermatologie et de venereologie
- Publication Type :
- Academic Journal
- Accession number :
- 31831216
- Full Text :
- https://doi.org/10.1016/j.annder.2019.09.605