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Approach to overgrowth syndromes in the genome era.

Authors :
Burkardt DD
Tatton-Brown K
Dobyns W
Graham JM Jr
Source :
American journal of medical genetics. Part C, Seminars in medical genetics [Am J Med Genet C Semin Med Genet] 2019 Dec; Vol. 181 (4), pp. 483-490. Date of Electronic Publication: 2019 Dec 02.
Publication Year :
2019

Abstract

This introduction to the special issue of AJMG Part C: Overgrowth Syndromes updates the current understanding of overgrowth syndromes. We clarify the terminology associated with overgrowth, review some common pathways to overgrowth and present a preliminary classification based on currently known genomic and epigenetic mechanisms. We introduce the articles of this issue-new research and reviews of well-established and recently described overgrowth syndromes of the brain, body or both.<br /> (© 2019 Wiley Periodicals, Inc.)

Details

Language :
English
ISSN :
1552-4876
Volume :
181
Issue :
4
Database :
MEDLINE
Journal :
American journal of medical genetics. Part C, Seminars in medical genetics
Publication Type :
Academic Journal
Accession number :
31793186
Full Text :
https://doi.org/10.1002/ajmg.c.31757