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The global burden of trichiasis in 2016.

Authors :
Flueckiger RM
Courtright P
Abdala M
Abdou A
Abdulnafea Z
Al-Khatib TK
Amer K
Amiel ON
Awoussi S
Bakhtiari A
Batcho W
Bella AL
Bennawi KH
Brooker SJ
Chu BK
Dejene M
Dezoumbe D
Elshafie BE
Elvis AA
Fabrice DN
Omar FJ
François M
François D
Garap J
Gichangi M
Goepogui A
Hammou J
Kadri B
Kabona G
Kabore M
Kalua K
Kamugisha M
Kebede B
Keita K
Khan AA
Kiflu G
Yibi M
Mackline G
Macleod C
Manangazira P
Masika MP
Massangaie M
Mduluza T
Meno N
Midzi N
Minnih AO
Mishra S
Mpyet C
Muraguri N
Mwingira U
Nassirou B
Ndjemba J
Nieba C
Ngondi J
Olobio N
Pavluck A
Phiri I
Pullan R
Qureshi B
Sarr B
Seiha D
Chávez GMS
Sharma S
Sisaleumsak S
Southisombath K
Stevens G
Woldendrias AT
Traoré L
Turyaguma P
Willis R
Yaya G
Yeo S
Zambroni F
Zhao J
Solomon AW
Source :
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2019 Nov 25; Vol. 13 (11), pp. e0007835. Date of Electronic Publication: 2019 Nov 25 (Print Publication: 2019).
Publication Year :
2019

Abstract

Background: Trichiasis is present when one or more eyelashes touches the eye. Uncorrected, it can cause blindness. Accurate estimates of numbers affected, and their geographical distribution, help guide resource allocation.<br />Methods: We obtained district-level trichiasis prevalence estimates in adults for 44 endemic and previously-endemic countries. We used (1) the most recent data for a district, if more than one estimate was available; (2) age- and sex-standardized corrections of historic estimates, where raw data were available; (3) historic estimates adjusted using a mean adjustment factor for districts where raw data were unavailable; and (4) expert assessment of available data for districts for which no prevalence estimates were available.<br />Findings: Internally age- and sex-standardized data represented 1,355 districts and contributed 662 thousand cases (95% confidence interval [CI] 324 thousand-1.1 million) to the global total. Age- and sex-standardized district-level prevalence estimates differed from raw estimates by a mean factor of 0.45 (range 0.03-2.28). Previously non- stratified estimates for 398 districts, adjusted by ×0.45, contributed a further 411 thousand cases (95% CI 283-557 thousand). Eight countries retained previous estimates, contributing 848 thousand cases (95% CI 225 thousand-1.7 million). New expert assessments in 14 countries contributed 862 thousand cases (95% CI 228 thousand-1.7 million). The global trichiasis burden in 2016 was 2.8 million cases (95% CI 1.1-5.2 million).<br />Interpretation: The 2016 estimate is lower than previous estimates, probably due to more and better data; scale-up of trichiasis management services; and reductions in incidence due to lower active trachoma prevalence.<br />Competing Interests: The authors have declared that no competing interests exist.

Details

Language :
English
ISSN :
1935-2735
Volume :
13
Issue :
11
Database :
MEDLINE
Journal :
PLoS neglected tropical diseases
Publication Type :
Academic Journal
Accession number :
31765415
Full Text :
https://doi.org/10.1371/journal.pntd.0007835