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Surgical outcomes of vitrectomy surgery for proliferative diabetic retinopathy in patients with abnormal renal function.
- Source :
-
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2020 Jan; Vol. 258 (1), pp. 63-70. Date of Electronic Publication: 2019 Nov 22. - Publication Year :
- 2020
-
Abstract
- Purpose: To analyse the influence of renal function on the outcomes of vitrectomy for tractional-related complications in cases of severe proliferative diabetic retinopathy (PDR).<br />Methods: Retrospective consecutive case series of 109 eyes that underwent vitreoretinal interventions for traction-related complications of severe PDR from 2014 to 2017. Data collected included patient demographics, best-corrected visual acuity (BCVA), surgical complications, and systemic markers including HbA1c and estimated glomerular filtration rate (eGFR). Renal function categories were defined as low (eGFR < 30 mL/min/1.73 m <superscript>2</superscript> ), medium (eGFR 30-60 mL/min/1.73 m <superscript>2</superscript> ), and normal (eGFR > 60 mL/min/1.73m  <superscript>2</superscript> ).<br />Results: A total of 109 eyes (56% (n = 61) female) were included in the study. Overall, mean baseline BCVA improved from 1.33 logMAR to 0.91 logMAR (p < 0.001) postoperatively. Patients with low eGFR had significantly worse baseline BCVA (p = 0.039) and demonstrated greater improvement in mean BCVA (p = 0.059). Multivariate regression analysis indicated that seven predictors explained 65.5% of the variance (R <superscript>2</superscript> = 0.655, F(11,97) = 16.7, p < 0.01).<br />Conclusions: Reduced renal function does not adversely affect visual outcomes of vitrectomy for traction-related complications of PDR.
- Subjects :
- Adult
Aged
Diabetic Retinopathy complications
Diabetic Retinopathy diagnosis
Female
Follow-Up Studies
Humans
Male
Middle Aged
Retrospective Studies
Treatment Outcome
Vitreoretinopathy, Proliferative diagnosis
Vitreoretinopathy, Proliferative etiology
Young Adult
Diabetic Retinopathy surgery
Visual Acuity
Vitrectomy methods
Vitreoretinopathy, Proliferative surgery
Subjects
Details
- Language :
- English
- ISSN :
- 1435-702X
- Volume :
- 258
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
- Publication Type :
- Academic Journal
- Accession number :
- 31758258
- Full Text :
- https://doi.org/10.1007/s00417-019-04532-7